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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRB2
All Species:
18.79
Human Site:
S246
Identified Species:
41.33
UniProt:
P07550
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07550
NP_000015.1
413
46427
S246
R
F
H
V
Q
N
L
S
Q
V
E
Q
D
G
R
Chimpanzee
Pan troglodytes
XP_527068
720
79546
S553
R
F
H
V
Q
N
L
S
Q
V
E
Q
D
G
R
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
S246
R
F
H
A
Q
N
L
S
Q
V
E
Q
D
G
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P18762
418
46984
S246
R
F
H
A
Q
N
L
S
Q
V
E
Q
D
G
R
Rat
Rattus norvegicus
P10608
418
46873
S246
R
F
H
A
Q
N
L
S
Q
V
E
Q
D
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513543
477
52086
P304
P
S
F
P
C
Q
P
P
P
S
G
L
P
N
G
Chicken
Gallus gallus
XP_425195
397
44745
E243
R
F
H
I
Q
N
K
E
Q
D
Q
N
G
K
A
Frog
Xenopus laevis
O42574
385
43291
M233
F
K
E
A
Q
K
Q
M
K
K
I
D
K
C
E
Zebra Danio
Brachydanio rerio
NP_001096122
405
46098
N244
A
Q
K
S
N
S
R
N
Q
D
V
A
N
N
H
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
H243
A
E
S
A
Q
N
R
H
S
S
M
G
N
S
L
Fruit Fly
Dros. melanogaster
Q4LBB9
536
60360
T384
S
G
S
S
K
T
L
T
L
H
E
V
E
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57
97.5
N.A.
N.A.
86.8
87.3
N.A.
45.7
70.9
51.3
54.4
33.9
30.7
N.A.
N.A.
N.A.
Protein Similarity:
100
57.2
98.3
N.A.
N.A.
91.1
91.6
N.A.
58.7
79.6
65.3
70.4
50.7
44.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
0
40
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
0
53.3
13.3
26.6
20
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
46
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
19
0
10
46
0
0
% D
% Glu:
0
10
10
0
0
0
0
10
0
0
55
0
10
0
19
% E
% Phe:
10
55
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
10
10
46
10
% G
% His:
0
0
55
0
0
0
0
10
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
10
0
10
10
10
0
10
10
0
0
10
10
0
% K
% Leu:
0
0
0
0
0
0
55
0
10
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
64
0
10
0
0
0
10
19
19
0
% N
% Pro:
10
0
0
10
0
0
10
10
10
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
73
10
10
0
64
0
10
46
0
10
0
% Q
% Arg:
55
0
0
0
0
0
19
0
0
0
0
0
0
0
46
% R
% Ser:
10
10
19
19
0
10
0
46
10
19
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
46
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _